Kinship Circle: Franken-Goats? Say No To Animals As Drug Machines

July 13th, 2008 5:05 pm by Kelly Garbato

———- Forwarded message ———-
From: Kinship Circle – kinshipcircle [at] accessus.net
Date: Fri, Jul 11, 2008 at 12:01 PM
Subject: Franken-Goats? Say No To Animals As Drug Machines

KINSHIP CIRCLE PRIMARY – PERMISSION TO CROSS-POST AS WRITTEN

7/11/08: Franken-Goats? Say No To Animals As Drug Machines

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Kinship Circle - 2008-07-11 - Franken-Goats

Some animal biologists say biotech companies oversell the safety of drugs from transgenic animals. Meanwhile, ethicists question whether we should restyle animals as drug producers at all…” Old McDonald had a pharm: http://www.salon.com/news/feature/2008/06/11/transgenic_goats/print.html
Photo courtesy of Kinship Circle

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FULL CONTACT INFORMATION. Sample letter follows.

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Dr. Andrew C. von Eschenbach, Commissioner
U.S. Food and Drug Administration
5600 Fishers Lane; Rockville, Maryland 20857
email: andrew.voneschenbach [at] fda.hhs.gov
web mail: http://www.fda.gov/comments/webform.html

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SAMPLE LETTER — This letter is prepared to inform you about the issue.
Try to shorten and personalize your letter before sending.

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Dear Commissioner von Eschenbach,

Please consider my comments about the FDA’s evaluation of ATryn, an antithrombin from GTC Biotherapeutics developed to prevent blood clots. There are too many animal welfare and human safety issues to allow Atryn and other transgenic drugs on the market.

To manufacture Atryn, GTC inserts a human gene into the DNA of goat embryos. For every 100 attempts at pronuclear injection, only one to 10 animals effectively become transgenic offspring. The 90 to 99 percent of animals who fail to assimilate the key gene are killed.

While GTC’s nuclear-transfer process prompts a higher rate of viable transgenic goats, offspring may have severe birth defects. Scientists have no solid explanation for why a transgene misses its targeted section of the genome and results in a malformed baby goat.

Using goats as “drug factories” raises significant concerns about reliability. If scientists cannot explain birth defects in goats, they cannot accurately predict allergic effects in humans who ingest ATryn. U.S. deaths or injuries linked to drug therapies more than doubled from 1998 to 2005, according to recent findings in the Archives of Internal Medicine. The American Medical Association has cited adverse drug reactions (ADRs) as a leading cause of death in U.S.

Drugs derived from transgenic animals have the potential to pass harmful pathogens to humans and should not earn FDA approval. Moreover, with ongoing advances in animal-free technology, it is unethical to introduce any drug rooted in animal suffering and exploitation.

Sincerely,

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KINSHIP CIRCLE OFF-LINE FROM JULY 17 – JULY 22

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KINSHIP CIRCLE WILL BE OFF-LINE: JULY 17 to JULY 22, 2008

Brenda Shoss and board member Bridget Soeder will present and exhibit at the Taking Action For Animals (TAFA) conference in Washington, DC.

Our workshop, “Internet Activism & The Power Of Words” is on Sunday, 7/20/08, from 2:45 to 3:45pm

The TAFA conference is held at the Hyatt Regency Crystal City in Arlington, Virginia. Tickets are still available. Read more about Taking Action For Animals — from July 19-21: http://www.takingactionforanimals.org

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SOURCE OF INFORMATION / REFERENCE LINKS

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Don’t Put Human Genes Into Goats for Drug Development!
http://www.thepetitionsite.com/takeaction/106751995?z00m=15445194

Medicine From Milk: Gene Therapy Could Transform Goats Into Pharmaceutical Factories
http://www.sciencedaily.com/releases/2008/01/080131082224.htm

Old McDonald had a pharm
http://www.salon.com/news/feature/2008/06/11/transgenic_goats/print.html

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